Endocan esm 1

Vascular endocan (ESM‐1) is markedly overexpressed in clear cell Vascular endocan (ESM‐1) is markedly overexpressed in clear cell renal cell carcinoma. Aims: In kidney cancer, new anti‐angiogenic therapies have emerged requiring parameters of effectiveness.

ESM1 (endothelial cell specific molecule 1), Authors: Dessen P. Published in: Atlas Genet Cytogenet Oncol Haematol. Other alias, endocan. HGNC (Hugo) Endocan emerged in the past years as a reliable prognostic factor in several The tissue and serum expression of Endocan (ESM-1) were measured using 14 Jan 2016 Objective: To investigate the level of endothelial cell specific molecule-1 (endocan) in obstructive sleep apnea (OSA). Methods: Study group ESM1 - Wikipedia The ESM-1 gene product is also called endocan since 2001, when it was characterized as a dermatan sulfate proteoglycan by Bechard et al. Recently, endocan / ESM-1 has been described as a specific biomarker of tip cells during neoangiogenesis by independent teams. Endocan/ESM-1 (300-062): ReliaTech Human ESM-1/Endocan should be reconstituted in 50 mM acetic acid or water to a concentration of 0.1 mg/ml.

29 Jul 2019 Running title: ESM1 and macrotrabecular-massive HCC. Keywords: Endocan, biomarker, angiogenesis, phenotype, immunohistochemistry.

Endocan/ESM-1 (300-062): ReliaTech Human ESM-1/Endocan should be reconstituted in 50 mM acetic acid or water to a concentration of 0.1 mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20 °C. Stability and Storage: The lyophilized human ESM-1/Endocan, though stable at room temperature, is best stored desiccated below 0 °C. Synonyms Endocan/ESM-1 Products: R&D Systems Endocan/ESM-1: Products Endocan, also known as Endothelial Cell-specific Molecule-1 (ESM-1) and IGFBP-rp6, is a secreted cysteine-rich dermatan sulfate proteoglycan.

The source of ESM-1 is probably not the placenta, but most likely maternal endothelial cells. Serial endocan concentration meets the major requirements for predicting outcome in patients with severe sepsis. An assay of endocan concentration may be a good prognostic biomarker in the clinic for severe sepsis.

It is primarily expressed by endothelial cells within the vascular network of the kidney and in the alveolar walls of the lung. ESM-1 (Endocan), human, recombinant (InC) | PromoCell Circulating Endocan can be detected in the serum from healthy subjects. In patients with lung cancer or acute and severe sepsis, elevated Endocan concentrations have been reported. Recombinant human Endocan is a 21.17 kDa protein containing 173 amino acid residues. Endocan or endothelial cell specific molecule-1 (ESM-1): a 1. Biochim Biophys Acta. 2006 Jan;1765(1):25-37.

Avoid repeated freeze-thaw cycles. Applications Human recombinant Endocan / ESM-1 (50 kDa) Carrying a unique DS / DS chain For research use only Endocan also called endothelial cell specific molecule 1 (ESM-1) is a Endocan / ESM-1 references on Cancers - COSMO BIO Publications related to Cancers (December 2012) Endocan / ESM-1 references on Cancers Publications in 2012 Roudnicky F, Poyet C, Wild P, Krampitz S, Negrini F, Huggenberger R, Rogler A, Stöhr R, Endocan / ESM-1 references on Sepsis - COSMO BIO Publications related to Sepsis (December 2012) 1 Endocan / ESM-1 references on Sepsis Publications in 2013 De Freitas Caires N., Legendre B, Parmentier E, Scherpereel A, Tsicopoulos A, Mathieu D, Lassalle P Endocan/ESM-1 (103-PA44S): ReliaTech Endocan is expressed by endothelial cells, adipocytes, bronchial epithelium and distal renal tubular epithelium. It is upregulated by TNFα and VEGF, and is known to bind to LFA1 (integrin αLβ2) on the surface of PBMCs, blocking LFA1 interaction with ICAM1. Normal circulating levels of Endocan are approximately 1 ng/mL.

The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium Evaluation of VEGF, VEGFR 1-2-3 and Endocan/ESM-1 Expression in Endocan, also called endothelial cell specific molecule-1 (ESM-1), has been shown to be expressed by endothelial tumor cells and especially by tip cells during angiogenesis. Endocan is highly up-regulated by pro-angiogenic molecules, such as VEGF.

Endocan/ESM‑1 was detected in perfusion fixed frozen sections of mouse embryo (13 d.p.c.) using Goat Anti-Mouse Endocan/ESM‑1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1999) at 5 µg/mL overnight at 4 °C. Endocan / ESM-1 Biotinylated Antibody | R&D Systems BAF1810 The Human Endocan/ESM-1 Biotinylated Antibody from R D Systems is a goat polyclonal antibody to Endocan/ESM-1.

Endocan/ESM-1 Antibody [Unconjugated] (AF1999): Novus Biologicals Endocan (endothelial cell proteoglycan; also known as endothelial-cell specific molecule-1 [ESM-1]), is a 50 kDa, monomeric, secreted, cysteine-rich proteoglycan identified initially in endothelial cells of the kidney and lung (1). ESM1 endothelial cell specific molecule 1 [ (human)] 24.09.2017 · endothelial cell-specific molecule 1, ESM-1. GeneRIFs: Gene References Into Functions. These findings provide the first evidence that the imbalance of MMP-9/TIMP-1, is one of the regulation mechanisms by which ESM1 promotes tumorigenicity and metastasis of prostate cancer cells. Endocan/ESM-1 Antibody (RM0079-5J44) (NBP1-21710): Novus There are currently no images for Endocan/ESM-1 Antibody (NBP1-21710).

2006 Jan;1765(1):25-37. Epub 2005 Aug 26. Endocan or endothelial cell specific molecule-1 (ESM-1): a potential novel endothelial cell marker and a new target for cancer therapy. Endocan or endothelial cell specific molecule-1 (ESM-1): A Endocan, previously called endothelial cell specific molecule-1, is a soluble proteoglycan of 50 kDa, constituted of a mature polypeptide of 165 amino acids and a single dermatan sulphate chain covalently linked to the serine residue at position 137. ESM1 Gene - GeneCards | ESM1 Protein | ESM1 Antibody Human Endocan/ESM-1 (NP_008967) VersaClone cDNA (RDC2039) Learn more about R&D Systems custom ESM1 antibody, protein, and immunoassay development services OriGene Antibodies for ESM1 Recombinant Human Endocan/ESM-1 (C-6His) | Novoprotein Recombinant Human ESM-1 is produced by our Mammalian expression system and the target gene encoding Trp20-Arg184 is expressed with a 6His tag at the C-terminus.

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Further research confirmed that ESM-1 belongs to the PGs family and consequently termed as endocan.